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Although temozolomide was being used clinically for melanoma in the mid-1990s, supported by substantial experimental data (Bleehen et al, 1995), there were no such animal data on temozolomide for brain tumours.
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Substantial experimental data also suggest that COX inhibitors might be effective chemopreventive agents for patients with BE.
Substantial experimental data suggest that the dose response relationship for health effects of formaldehyde is nonlinear (Nielsen and Wolkoff 2010).
13 Substantial experimental data in animals and humans indicate that L-arginine could have a beneficial effect on haemodynamics.
Many of these viewpoints have been supported by substantial experimental evidence.
The method is validated by numerical simulations and by experimental data obtained using a microtubule sample.
This notion has been supported by some experimental data.
This prediction was confirmed by the experimental data.
The important results from the substantial body of experimental data on the formation of poly(1,4-phenylene sulfide) by polymerization of copper(I) 4-bromobenzenethiolate (CBT) have been documented.
In a previous study, a substantial simplification of the aforesaid procedure was achieved, by correlating the experimental data with an empirical formula, allowing to obtain a mathematical description of the boundaries of the flammable cloud.
This is the first time that results obtained from SRS have been compared against a substantial amount of experimental data.
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