In our patient series, ASV significantly improved dys-synchrony by using measured dynamic compliance and time constant cycle by cycle with subsequent optimization of flow time curves with less use of sedation and neuromuscular blockage.
The solutions obtained provide good initial points for subsequent optimization by rigorous minlp solution methods.
The mergence of the two parameters was accomplished using the Derringer's desirability function with subsequent optimization by a Box Behnken response surface design.
A subsequent optimization by median filtering results in final estimates.
We have proved in Section 4 that a subsequent optimization by median filtering of the substitute set takes the current noisy pixel closer to original noise-free image pixel.
We then constructed 50 different conformations of hTAS2R38 (that were obtained with randomized initial structures and subsequent optimization by conjugate gradients and simulated annealing) based on each of the eight structural templates using Modeller9v3 [35].
Subsequent optimization by removing residue repeat 19 in the Δ17 48 minigene resulted in a more protective ΔH2-R19 minigene (Fig. 4B) (Harper et al., 2002).
Subsequent optimization guided by c-Met-inhibitor X-ray structures furnished new compound classes with excellent in vitro and in vivo profiles.
The subsequent optimization is done by a cost function introduced below which incorporates stereo and temporal matching (Equation 6).
