Sentence examples for by subsequent activation of from inspiring English sources
Typically, activation of critical pathways is accompanied by subsequent activation of negative feedback loops reducing pathway activity.
We wished to determine whether the effect of D2R activation was reversible, and whether inhibited mitochondria could be re-induced to move by subsequent activation of D1R within the same neuron.
This results in the inhibition of apoptosis by subsequent activation of the expression of inhibitor of apoptosis proteins (IAPs).
At all stages of the fibrogenesis, the stress exerted on the liver parenchyma is exemplified by subsequent activation of the immune system accompanied by increased levels of certain cytokines and growth factors, which augment fibrogenesis.
Remarkably, Rm-HE treatment rapidly led to procaspase 8 cleavage, which is indicative of activation of the extrinsic apoptotic pathway, an event that was followed by subsequent activation of caspase 9.
Specifically, under conditions of high Bcl2 and 20%% pre-activation of mitophagy, followed by subsequent activation of apoptosis by tBid, the model parameters were qualitatively calibrated to experimental observations.
These findings suggest the pathological outcome of the liver in ConA-treated animals relies on initial activation of innate immune components, such as NK T cells, followed by subsequent activation and recruitment of effector immune cells, including macrophages and T-cells.
Is there a sequential aspect to the process whereby for example following recruitment of Gbf1 by TRAPPI, subsequent activation of Rab1b by Gbf1 requires dissociation of TRAPPI?
The high expression of a ligand that activates the Notch1 signalling pathway (Jagged 1) was noted in hypertrophic astrocytes and postulated to inhibit oligodendrocyte differentiation via secretion of Jagged 1 by astrocytes, subsequent activation of the Notch pathway, followed by inhibition of OPC differentiation.
The study suggests that this detrimental process is driven by A β binding to Ca-ARs at the dendritic surface and by the subsequent activation of calcineurin, an event that leads to the internalization of A β and AMPARs.
DC capture, process and present antigen bound to MHC for recognition by and subsequent activation of T cells [1].
