Sentence examples for by sublethal doses of from inspiring English sources

First, we examined whether p38 is activated by sublethal doses of H2O2 in hMESCs.

Preconditioning can also be achieved by sublethal doses of N-methyl D-asparate (NMDA), which increased hippocampal CA1 neuron survival after ischemia, an effect blocked by the TrkB antagonist K252a [ 32].

We have also defined an important role for changes in the cellular redox state induced by sublethal doses of chemotherapy (melphalan, doxorubicin), in the control of DDR-dependent upregulation of ligand surface expression and gene transcriptional activity.

In this study, leptin expression was increased by sublethal dose of AA in kidney fibroblast NRK49f determined by enzyme-linked immunosorbent assay and Western blot.

In addition, Rangoonwala et al. [ 66] observed a progressive hypocalcemia in rats treated by sublethal dose of DZN.

This effect is already induced by sublethal doses.

Several evidences have demonstrated that differentiated cells can recover after MOMP (Martinou et al., 1999; Deshmukh et al., 2000; Tang et al., 2009) and our study identifies Apaf1 and autophagy induction as part of the molecular mechanism of the recovery process, in particular in cells affected by hypoxic or sublethal doses of intrinsic apoptosis inducers.

Human umbilical vein endothelial cells, PrSC, RPTEC, and CD8+ T lymphocytes were treated by exposure to sublethal doses of tBHP (Unterluggauer et al., 2003).

Resistance to Fas-mediated cytotoxicity could be overcome in DU145, but not in LNCaP, cells by pretreating cells with sublethal doses of cytotoxic drugs, such as camptothecin.

By extending our previous findings on melanoma cell sensitization toward TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) by co-application of sublethal doses of ultraviolet-B radiation (UVB) or cisplatin, we show significant differences in the therapeutical outcome to exist between regular two-dimensional (2D) and complex in vivo-like 3D models.

We have previously shown that the androgen-independent prostate cancer cells DU145, despite expressing Fas and FasL, were resistant to anti-Fas-induced apoptosis, and that this resistance could be overcome by pretreating the cells with sublethal doses of camptothecin.