Sentence examples for by structural modifications in from inspiring English sources

These predictions are, therefore, directly testable experimentally by structural modifications, in a manner that can validate the important insights about the mechanistic involvement of PIP2 in the functionally critical phosphorylation of STX.

Herein, a series of pyrimidine-carbothioamide derivatives 4 a-t) was designed as anticonvulsant agents by doing some important structural modifications in well-known anticonvulsant drugs.

We could demonstrate that all parameters can be significantly improved by structural modifications resulting in BI 414 as a potent and orally available MCH-R1 antagonist tool compound with acceptable in vivo efficacy in an animal model of obesity.

The fluorescent properties of fluorescein (1) can be tuned by structural modifications, as shown in Figure 1C.

The appropriate duration of persistence is normally achieved by structural modifications that improve stability in light without compromising biodegradability.

The redesign of GST A1-1 into GIMFhelix therefore serves as an illustration of divergent evolution leading to novel enzymes by minor structural modifications in the active site.

A long-standing hypothesis is that altered synaptic strength is maintained by structural modifications to synapses.

Experiences in the development of CXCR4-targeting peptides showed that affinities to the CXCR4 receptor can be significantly affected by even moderate structural modifications in the pentapeptide core [16 19], the linker unit [20], or the chelate [7, 8].

That choice was driven by considerable possibilities of introducing structural modifications in cationomers and by general environmental compatibility of waterborne polyurethanes.

Due to their extremely high copy numbers, REs create structural modifications in the genome by providing the requisite highly similar DNA sequences, initiating recombination between non-allelic elements [ 20, 25, 60], the result of which could be deletion, shuffling, duplication or transduction of a genomic DNA segment.

Structural modifications in the carbon nanotubes were confirmed by Fourier transform infrared spectroscopy.