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The dramatic difference in model performance between the test and the validated training sets can be explained by structural dissimilarity of the sets.
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The sequence and structural dissimilarity of the predicted Streptomyces sRNAs demonstrated by this study serve as the first evidence of the uniqueness of Actinomyces sRNAs.
The number was surprisingly high, suggesting strong sequence and structural dissimilarity of Streptomyces sRNAs.
The rate of α-pinene release was assayed (Table 1) and interestingly, the mutants that improved efflux of n-octane also enhanced the efflux rate of α-pinene (Table 1) despite the structural dissimilarity of the substrates.
The identified non-conserved regions and structural dissimilarities of Rab7/Rab9 proteins may be a good starting point to further functional and structural studies.
The differences observed in tobacco are in contrast to the results obtained with fixed tissue of A. thaliana, where no structural dissimilarities of actin were detected between leaves treated with wBL or SBL [ 27].
Figure 10 Structural dissimilarity map of the first two frames of the continuous-tone caltrain sequence.
Interestingly, a dendrogram generated solely on the basis of structural dissimilarity measure at the level of domain folds was found to cluster functionally similar members.
Here, we investigate different ways of obtaining localized measures of structural dissimilarity and describe RNAsnp, a tool geared toward evaluating SNP effects on large data sets that is more sensitive to local structural change than the available methods.
The other three promiscuous substrates, 11-phenoxyundecanoic acid (11PA), 2-phenoxyethanol (2PE), and 1,2-methylenedioxybenzene (MDOB), are organic compounds of increasing structural dissimilarity to 12-pNCA.
The 3-D superimposition of protein structures obtained by using structure comparison tools is very useful in quantifying structural dissimilarity and in analyzing structural divergence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com