Sentence examples for by structural destabilization of from inspiring English sources

Metal ions such as Cd2+, Co2+, and Hg2+ act on sulfhydryl residues in proteins and are responsible for a breakdown of disulfide bonds, generally causing a strong inhibitory effect on enzymatic activity by structural destabilization of the protein [34].

Substitution of these residues inevitably causes a structural destabilization of the LRR domain.

Structural destabilization of wild-type and L55P, V30M and V122I TTR variants might enable proteolytic cleavage of the protein.

This causes clustering of positive charges around Lys112 and Lys115, and may result in structural destabilization by electrostatic repulsion and undesired interactions with negatively-charged molecules.

The higher initial fluo-rescence observed from F637S may indicate partial structural destabilization by this mutation.

The structural destabilization and the surface porosity of wild grass were more pronounced after steam explosion) than after alkali (NaOH) pretreatment).

This enabled us to observe the differential decrease of residual activity among mutants due to structural destabilization during the heat treatment processes.

Urea breaks hydrogen bonds among biopolymers leading to structural destabilization.

However, the present results indicate that the alteration of the partitioning by NaSCN was induced by destabilization of the SWCNTs.

Apoptosis can also be triggered by the destabilization of F-actin structures.

This was confirmed by the destabilization of the warfarin binding site.