Sentence examples for by stimulating the binding from inspiring English sources

Therefore we propose that EphrinB2 signaling would promote epithelialization in two complementary ways: (1) by lowering the activity of Cdc42 promoting epithelialization [69] and (2) by stimulating the binding of caudal s0 cells to the FN matrix which, in turn, induces N-cadherin polarization, cell elongation and centripetal alignment.

SmpB promotes RNase R proteolysis by stimulating the binding of Lon and HslUV proteases [ 40].

TNF α via NF κB signaling stimulates aromatase expression through CYP19A1 (aromatase) promoter I.4 by stimulating the binding of c-Fos and c-Jun transcription factors to the activation protein-1 (AP-1) element upstream of promoter I.4, while PGE2 stimulates aromatase expression through promoter II/I.3 of the human CYP19A1 gene [ 13].

Another representative example is the module (7 members) characterized by the eIF3 (7 members) complex, which is responsible among with other eIFs for the initiation of protein synthesis in eukaryotic cells by stimulating the binding of mRNA and methionyl-initiator tRNA (tRNAi-Met) to 40S ribosomes to form the 48S pre-initiation complex [ 48].

NPM enhances p53 activity directly by binding to and stabilizing p53 or indirectly by stimulating the induction of p53 through binding to other p53 regulators, such as HDM2 and ARF [ 118– 118].

By virtue of its broader somatostatin receptor affinity profile, however, pasireotide also potently inhibits IGF-I activity directly in the mammary gland, likely by stimulating the expression of IGF-I binding protein 5, which preferentially binds to IGF-I making it unavailable for its receptor [ 12].

Work over the last decades revealed that Ca2+ binding to synaptotagmin triggers release by stimulating synaptotagmin binding to a core fusion machinery composed of SNARE and SM proteins that mediates membrane fusion during exocytosis.

In normal cells, EGFR activates RAS by stimulating its binding to GTP.

TBI induces the expression of GADD34 by stimulating binding of a stress inducible transcription factor, ATF4, to the GADD34 promoter.

CXCR4 is known to promote cell adhesion by stimulating binding of integrins, such as α4β1 and αLβ2, to their respective ligands [39].

Renoux et al. [ 15] have reported that NK cells are stimulated by the binding of HPV-specific VLPs via C16 receptor to higher cytotoxicity and increased cytokines production.