Sentence examples for by stimulating secretion of from inspiring English sources

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The cytokines involved, including IL-1 and TNF-α, have direct and indirect pro-inflammatory effects to regulate the degradation of ECM components by stimulating secretion of proteolytic enzymes and other mediators, such as MMPs, aggrecanases and other members of the 'a disintegrin and metallo-proteinase with thrombospondin motifs' (ADAMTS) gene family, NO, and prostaglandin E2 [ 149, 177, 178].

An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligand.

Moreover, it probably plays an important role in the pathogenesis of SLE by stimulating secretion of the chemokines IP-10, MIG and IL-8.

They provide evidence that protection is mediated by upregulation of PDGFRβ, a signalling factor that promotes lung development and alveolar maintenance by stimulating secretion of keratinocyte growth factor and expression of elastin.

Similar(56)

FSTL1 exerts its proinflammatory role by changing the microenvironment of synoviocytes and directly stimulating secretion of inflammatory cytokines by FLS.

SPARC may promote vascularisation of tumours, tumour progression, or invasiveness by modulating the activity of cytokines and stimulating secretion of tissue remodelling metalloproteases (Lane and Sage, 1994; Motamed and Sage, 1997; Sage, 1997).

Insulin can increase blood volume through stimulating secretion of vasopressin (an antidiuretic) (30) and renal sodium retention (31).

We hypothesised that exogenous GIP will lower fasting and nutrient-stimulated glycaemia by stimulating insulin secretion, while modestly accelerating gastric emptying, and increasing the rate of glucose absorption.

In the pancreas GLP-1 plays an essential role in glucose homeostasis by stimulating insulin secretion and inhibiting glucagon secretion.

CONCLUSIONS Vildagliptin lowers postprandial glucose concentrations by stimulating insulin secretion and suppressing glucagon secretion but not by altered insulin action or glucose effectiveness.

Sulfonylureas are insulin secretagogues that appear to work by stimulating insulin secretion from beta cells of the pancreas.

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