Sentence examples for by stem cells factor from inspiring English sources

The intrastriatal NPC transplantation in 6-OHDA-induced experimental PD rats induced behavioural recovery and protected from dopaminergic depletion by stem cells factor (SCF -mediated anti-apoptotic effectSCF -mediated

However in small cell lung cancer was demonstrated that the activation of c-kit by stem cells factor (SCF) leads to a predominantly HIF-1-alpha-mediated enhancement of VEGF expression and that inhibition of c-kit signalling with imatinib could result in inhibition of tumor angiogenesis [ 40].

Activation of c-Kit by stem cell factor results in Mitf phosphorilation [8].

In Figure 2 we show an example to calculating the consistency value of an interaction taken from the pathway "Signaling events mediated by Stem cell factor receptor (c-Kit)", one of the NCI-Nature Curated pathways from the Pathway Interaction Database (PID [27].

We previously demonstrated that nilotinib-induced apoptosis was reduced by stem cell factor (SCF) addition.

The KIT gene (CD117) codes for a type III tyrosine-kinase receptor activated by stem cell factor (SCF).

The growth of MCs is mainly influenced by stem cell factor (SCF), which is produced by stromal cells, endothelial cells, and fibroblasts [ 80].

In contrast, Erk activation induced by stem cell factor, which activates c-Kit in the same cells, is sensitive to Raf inhibition and insensitive to PI3K and PKC inhibitors.

KIT encodes a receptor tyrosine kinase that is activated by stem cell factor binding and initiates numerous signal transduction pathways linked with the process of apoptosis, proliferation and tumorigenesis [ 31].

Using patch clamp recording we have been unable to identify any Kir-like currents in HLMC (manuscript submitted), but as mast cells require activation by stem cell factor for survival and Kir 2.0 channels may be closed by tyrosine phosphorylation [ 11], it is possible that the channels are closed under basal conditions.

These signalling mechanisms include activation of receptor tyrosine kinase CD117 (c-kit) on the surface of erythroid progenitor cells by stem cell factor (c-kit ligand), which has a key role in HbF reactivation in adult life (Wojda et al, 2003; Bhnu et al, 2004; Gabbianelli et al, 2010).