As predicted by statistical principles, we found that putative recombinants formed separated clades.
Furthermore, by clarifying the statistical principles of MYCN amplicon segregation, we have now acquired a precise standard against which the effects of potential anti-neuroblastoma drugs acting through MYCN amplicon elimination can be compared.
However, it should indicate that the SPC is a statistical principle of hypothesis testing.
Extensive literature now in existence [4] [6] describes specific methods (e.g., bootstrap and jackknife), developed by a number of scholars, and offers sophisticated arguments, based on sound statistical principles, in support of those methods.
This recognition of the key role of statistical principles in study design and analysis has resulted in integrated and critical involvement by statisticians in all aspects of clinical trials.
Medicine's most prestigious journal took up this torch last week by publishing an article that used a complex explanation of statistical principles to make the same point.
The introduction of the ICH guideline "Statistical Principles for Clinical Trials", adopted by the regulatory bodies of the European Union, Japan, and the USA in 1998, was, for example, the first time that clear and consistent regulatory guidance on statistical principles had been made available internationally.
The NIH peer review structure has not been based in rigorous applications of statistical principles involving sampling [4].
Due to its simplicity, the approach does not require a sophisticated understanding of statistical principles.
By using experimental designs based on statistical principles, researchers can extract, from a minimum number of experiments, a maximum of useful information about the system under study.
