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This visit will consist of the risk communication intervention (see below) followed by standard care of DCS.
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The gray-shaded areas in Figure 4 represent the predicted PANSS improvements by either placebo or the standard care of antipsychotics alone ranging from 10 to 23 points, which are generally consistent with the reported clinical efficacy of these antipsychotics.
The two community based cluster trials compared oral amoxicillin administered at home by community health workers to administration of cotrimoxazole in the community followed by standard of care of receiving parenteral therapy at hospital.
This exactly describes the current study's design, i.e. treatment of imatinib-resistant GIST with a regimen of masitinib followed by standard of care (sunitinib then other therapies) compared against the standard of care, indicating that the study findings have a methodologically sound basis.
In summary, this was a well-controlled and appropriately designed randomized clinical trial for comparing the efficacy and safety of masitinib followed by standard of care in imatinib-resistant GIST against the standard of care.
One major problem in preclinical arthritis research is a reliable assessment of symptom severity and its alleviation by standard of care medication in respective animal models to achieve a good translational potency for predicting clinical outcome.
Cytoreductive surgery will be performed in patients in whom it is indicated by standard of care.
In addition we worked with the Institute of Lung Health to understand disease expression showing that IL-13 was expressed not only by mild patients controlled by β-agonists alone (GINA1) but also those severe patients (GINA4-5) thareare currently insufficiently controlled by standard of care (Saha et al., 2008).
F-NaF PET/CT was found to be superior at detecting metastases compared with the other techniques, and detected a number of metastases that were not identified by standard-of-care imaging.
In the multiple attack studies, pain relief at 2 h was achieved in a significantly higher number of attacks treated with a rizatriptan 5-mg tablet (77%) or with a rizatriptan 5-mg wafer (77%) than by means of standard care (64%).
The impact on midwives' personal lives was mentioned by 25% of standard care midwives at baseline, and 15% after two years.
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