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If the model and/or the algorithm is inadequate, then sophisticated attacks that are triggered by specific sequences of events will not be detected.
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In a recent study [26] we examined p53 transactivation potential using various permutations of ½ site RE sequences, confirming that p53 transactivation from this type of noncanonical regulatory sequence is affected by specific sequence features of the RE, similar to what is observed for full-site (tetrameric) canonical REs.
Using video-recordings of a meal shared by a young child, his parents, and his grandparents, the paper examines how identities are made operative in and through the moment-by-moment organization of specific sequences of action.
(i) Proteins that regulate cellular metabolism by recognizing and binding specific sequences of DNA typically display specificity of multiple orders of magnitude for their targets.
These findings together with our data lead us to conclude that the nucleolar localization of L22 is likely mediated by its interaction with specific sequences of 28S rRNA.
We then identify the core genome regions most frequently affected by recombination, and the specific sequences of recombinant origin within epidemic strains.
This regulatable mode of transcription control therefore provides a useful way to determine the dependency of gene expression by tailor-made rTFs targeting specific sequences of genes.
The activity of genes is governed by transcription factors, which bind to specific sequences of DNA units that lie close to the gene.
Targeting signals of proteins are less constrained by specific sequence requirements than active sites of proteins, and therefore may be acquired and/or altered over time.
They are constituted by a specific sequence of amino acids within a codified spatial organization.
Upward and downward steps are made by a specific sequence of moving, opening and closing two internal clamps which are actuated using three subsystems.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com