Sentence examples for by specific isoforms of from inspiring English sources

However, we are reporting first time that MCP-induced apoptosis and oxidative stress are associated/regulated by specific isoforms of CYPs in PC12 cells.

Key mechanisms in the pathogenesis of vascular dysfunction in DN are ROS formation followed by the activation of specific isoforms of PKC.

The dumpy gene contains 78 coding exons, many are very small, i.e. under 80bp, and the number of nucleotides in all but 1 internal exon is divisible by 3. We predict and, indeed, have found that alternative splicing produces tissue specific isoforms of Dumpy encoded by at least several kinds of mRNAs.

We demonstrate that this activity is mediated by a specific isoform of DAF-16, DAF-16B.

Different consensus sequences might be bound by tissue-specific isoforms of CstF-RNA binding subunits [ 21] or competitor proteins [ 22].

The power of a more precise bin approach is illustrated by detection of a specific isoform of Adora 3 consisting of only two exons out of a total of 9 known for this locus and upregulated at the 3 hour time point (Additional file 6: Figure S3).

Four of these proteins are modulated only by the combined treatment: a specific isoform of HSPB1, dihydropyrimidinase-related protein 2 (Dphosphoglycerateycerate mutase 1 (PGand), and transgelin-2 (TAGL2).

We believe that the conflicting results uncovered by our group and others on the specific isoform of XBP-1 that is involved in the degradation of FoxO1 could be explained by the different cell lines used in the respective studies; cancer cell lines were used in our study, and MEFs were used in the other study.

Such limited co-localization indicates that assembly and bundling of nuclear EN-filaments are controlled by nuclear-specific regulators or nuclear-specific isoforms of actin-associated proteins.

This gene encodes a number of tissue-specific isoforms of dystrophin generated by transcription from at least seven promoters and also by alternative splicing.

Moreover, by using females constitutively expressing the male-specific isoforms of fru (FruM), we show a critical requirement for the male isoform of dsx (DsxM), alongside FruM, in the specification of courtship song.