Sentence examples for by specific cell surface from inspiring English sources

Many of the effects of LPA are mediated by specific cell surface receptors.

TIC can be characterized by specific cell surface marker expression patterns, such as lin−/CD44+/CD24− or ALDH1 expression [1], [2].

Their effects are mediated by specific cell surface receptors on the endothelium.

Wicha went on to show that breast cancers contain putative cancer stem cells that can be selected by specific cell surface markers such as CD44 and CD24.

It is mediated by specific cell surface lectins, able to bind directly to mannose residues of mannan molecules on adjacent cells.

The recognition and internalization of carbohydrate residues by specific cell surface carbohydrate-binding proteins play a crucial role in mediating the cellular uptake of many glycosylated natural products and control their biological activity.

Intercellular signaling by these chemokines is transduced by a specific cell surface receptor: the CC chemokine receptor 2 (CCR2).

The bacteriocin gains entry into the target cell by recognizing specific cell surface receptors and then kills the cell by forming ion-permeable channels in the cytoplasmic membrane, by nonspecific degradation of cellular DNA, by inhibition of protein synthesis through the specific cleavage of 16s rRNA, or by cell lysis resulting from inhibition of peptidoglycan synthesis.

These may include treatment strategies targeting altered genetic signalling pathways by blocking specific cell surface molecules, altering the cancer microenvironments that nurture cancer stem cells, inducing differentiation of CSCs, immunotherapy based on CSCs associated antigens, exploiting metabolites to kill CSCs, and designing small interfering RNA/DNA molecules that especially target CSCs.

These results are consistent with the hypothesis that apoE modulates microglial function by binding specific cell surface receptors and that the immunomodulatory effects of apoE in the central nervous system may account for its role in acute and chronic neurological disease.

The presence of PS at the outer membrane leaflet, as determined by a specific cell surface staining using the Ca2+-dependent phospholipid binding protein Annexin-V [30] serves as an early marker for apoptotic cell death [31].