Sentence examples for by single particle analysis from inspiring English sources

Thus far, protein complexes that have been successfully reconstructed to high resolution by single particle analysis (SPA) have molecular weights of ∼100 kDa or larger2.

The only means to accurately distinguish between the multiple compositions in APM is by single particle analysis.

From 2D image analysis, the 60S subunit and Sdo1p could form stable 60S-60S dimers, which should enable the 3D structural determination of dimers by single particle analysis.

To further analyze this PilQ-containing structure, a large data set of about 20,000 single projections of the stain-filled indentations was obtained from EM images and analyzed by single particle analysis.

(E ) 3D reconstruction of the Drosophila Tld monomer by single particle analysis electron microscopy shown in three orthogonal orientations.

For protein analysed by single particle analysis (see next section), an additional HPLC gel filtration step was included.

This motion blurs the images and limits the resolution attainable by single-particle analysis.

These results are consistent with the previous observation of two distinct oligomeric species by single-particle analysis of electron micrographs.

A number of recent technological advances in cryo-EM have permitted structure determination by single-particle analysis to unprecedented resolution (Bai et al., 2013; Li et al., 2013).

Our structure of the bovine heart F1Fo ATP synthase reconstituted into a lipid bilayer is consistent with the monomeric detergent-solubilised complex determined by single-particle analysis (Baker et al., 2012).

This hypothesis was also supported by a single particle analysis on complex I from E. coli in the presence of NADH or NAD+ [63].