Sentence examples for by single marker tests from inspiring English sources

Haplotype analysis may identify susceptibility loci that are not captured by single marker tests and/or reveal the combinatory effect of loci [23].

Compared with single marker tests, such as D-dimer, a multi-marker strategy may improve diagnostic ability.

Second, we applied the false discovery rate to quantify uncertainty across the multiple hypotheses tested in the six single marker tests and the multiple haplotype tests.

Previous studies have shown that single marker tests provide similar or greater power than haplotype-based approaches [57], [58].

Secondly, carrying out thousands of dependent single marker tests tends to produce many false positives.

Henceforth, traditional single marker tests that capture only marginal effects are doomed to have low power.

Using the binary BRDC case control phenotype, the EMMAX-GRM analyses were conducted using an additive model and consisted of single marker tests of association [ 21], with corresponding estimates for the proportion of variance explained (PVE) by effects at single markers, and utilized a genomic relationship matrix [ 23], rather than an IBS kinship matrix [ 21, 22].

This gene would be missed by both single marker test as well as ranking genes by posterior score.

Penalized regression methods offer an attractive alternative to single marker testing in genetic association analysis.

Each trait was initially investigated by single marker analysis.

The mapping was initiated by single marker mapping.