Sentence examples for by single cell transcriptome from inspiring English sources
For this reason, the differentiation changes might best be studied by single cell transcriptome analysis, which is outside the scope of this study.
These observations suggested that the slight transcriptional changes which may be masked in previously bulk cell analysis can be revealed by single cell transcriptome analysis.
(C) Cross-referencing gene expression of red, turquoise, and brown identified from our 22 single cell transcriptome, in published data set by Llorens-Bobadilla et al. in Cell Stem Cell (2015).
Open image in new window Figure 4 Single cell transcriptome analysis revealed maturation-related genes.
Open image in new window Open image in new window Figure 2 Single cell transcriptome analyses reveal neuronal property of collected target cells.
Coupled electrophysiological recording and single cell transcriptome analysis will serve as powerful tools in the future to unveil molecular logics for neural circuitry functions.
Taken together, through this proof of principle study we demonstrated the power of using single cell transcriptome analyses to reveal potential molecular mechanisms underlying NSC/NPCs aging.
Moreover, single cell transcriptome analyses revealed that different aged NSC/NPC subpopulations, while all have reduced cell proliferation, use different gene transcription programs to regulate age-dependent decline in cell cycle.
All these cells have previously been reported to exist in the NSC/NPC pool from EZ-SEZ/SVZ EZ-SEZ/SVZouse vin single cell tradultiptomousealyses (Luo et al., 2015; Llorens-Bobadilla et al., 2015; Dulken et al., 2017).
These data suggested that although single cell transcriptome profiling is prone to carrying lots of noises, when using large gene clusters to define cell type identity, the result could be quite unambiguous and can be cross-referenced among different studies.
