Sentence examples for by significant induction of from inspiring English sources

The anti-HLA class I induced AEC proliferation after 24 hours followed by significant induction of apoptosis after 48 hours.

Namely, HO-1 to EF2 reference gene ratio was 0.052±0.020 in AdGFP and 0.071±0.031 in AdHO-1 (P = 0.056) on day 1 and 0.054±0.026 in AdGFP and 0.065±0.009 (P = 0.230) on day 3. Possibly, transgene expression is masked by significant induction of endogenous enzyme in response to injury, as the HO-1/EF2 ratio in healthy skin was 0.013±0.012.

CCAO was followed by significant induction of collateral growth in the ipsilateral posterior cerebral artery (PCA), posterior communicating artery (PComA), the middle cerebral artery (MCA), and the anterior cerebral artery (ACA) of the circle of Willis and 1(b)).

We suspect that BG expression is not only driven by BC039389 increase, but that also GATM loss plays a role since such loss evokes an increase of BG expression, as reflected by the significant induction of BGv1 by 1.5- to 2-fold in the experiment with si GATMwt knock-down in ACHN and Caki-2 (Additional file 1: Figure S7A).

A role for NF-κB is further supported by the significant induction of IL23A mRNA by the NOD1 agonist D-glutamylmeso-diaminopimelic acid (iE-DAP).

Further studies revealed that the Mar-induced cell death was greatly associated with the activation of autophagy, as indicated by the significant induction of microtubule-associated protein-1 light chain-3 beta (LC3B) expression and conversion.

In particular, oral intake of PSP was found to have immunomodulatory effect in breast cancer patients, as evidenced by the significant induction of the T-helper lymphocytes and the B-lymphocytes [ 8].

In addition, quantitative RT-qPCR experiments demonstrated that this in vivo binding was accompanied by a significant induction of Hsp70 and Hsp90 transcription (1.78 and 1.70 fold, respectively; P < 0.005; n = 8; Fig  1D).

This was accompanied by a significant induction of the protein levels of mitochondrial HSP-60 in dOTC, pink1 and parkin mutants but not for the cytosolic HSP-70, supporting the view that accumulation of unfolded proteins in the mitochondrial compartment and loss of pink1 or parkin results in the selective upregulation of target genes encoding mitochondrial stress proteins in flies.

Furthermore, in accordance with publications of other groups describing Sox9 as regulated by HIF1, a significant induction of Sox9 expression could be determined in this experimentVI) [ 13, 35].

Extensions of these findings at the protein level by Western blot confirmed significant induction of COX2 or FN1 protein levels (Figure 4A and B).