Sentence examples for by severe side effects from inspiring English sources

However, therapeutic efficacy is often hampered by severe side effects and poor pharmacokinetic properties.

However, its use, at its full potential, is limited by severe side effects.

The therapeutic efficacy of cytokines is often hampered by severe side effects due to their undesired binding to healthy cells.

However, the platinum based treatment of tumoral diseases is massively hampered by severe side effects and resistance development.

Consistently, PPARγ agonists have been proposed in various inflammatory skin disorders, but their wide use has been limited by severe side effects.

The most efficacious compounds that induce muscle hypertrophy or endurance are hampered by severe side effects and are classified as doping.

High-dose IL-2 immunotherapy has been a promising treatment option for metastatic cancers but is often accompanied by severe side-effects such as pulmonary edema.

However, the clinical use of cytotoxic cancer drugs, which target uncontrolled, dividing cancer cells, is limited by the severe side effects caused by killing fast dividing normal cells, such as blood cells.

But, the success of chemotherapy is limited by its severe side effects and the development of multidrug resistance by the tumor cells.

The effect is often excellent, but use is hampered by the severe side effects associated with long-term treatment.

Vitamin D has been shown to display a wide variety of antitumour effects, but their therapeutic use is limited by its severe side effects.