Sentence examples for by setting cell death from inspiring English sources

By setting cell death receptors as starting point for the signaling pathway we constructed a model of the pathway to visualize the interactions.

The fact that inhibition of stress kinase signaling may be protective in the setting of ischemia/reperfusion by preventing cell death has been pointed out before.

Cell survival under DNA damage have sigmoid dose-response curve [ 16], we have modeled this observations by setting probability for p53 mediated cell death to be a sigmoid curve (2) r apopt = β D 2 D 2 + 1 Observe that the functional form in mutational and apoptotic probabilities are set to be the same as this allows most efficient elimination of mutated cells.

The extrinsic apoptosis pathway is triggered by extracellular cell death stimulation such as death ligands15.

Thus, lack of Hif1a may not affect cell proliferation but rescues rods by preventing cell death.

Mitochondria Released by Apoptotic Cell Death Initiate Innate Immune Responses.

Chondrocytes may die by necrosis (physical disruption of the cell) or by apoptosis (programed cell death).

This step leads to mitochondrial poisoning followed by cell death.

We speculate that disruption in cell membrane was probably induced by irradiation-induced cell death.

First, the BH3-only proteins Bim, Bad, and Hrk are induced by cytokine deprivation in a p53-independent manner [ 60], yet these proteins may synergize with p53-induced pathways to overcome the antiapoptotic threshold set by Bcl-2 and promote cell death.

Cell viability was performed by the trypan blue cell death assay.