Sentence examples for by setting a stringent from inspiring English sources
By setting a stringent cut-off requiring effects to be at least as potent as those of miR-149, we identified 43 miRNAs that specifically altered HRG-induced Akt activation, with 24 increasing and 19 decreasing Akt activation.
By setting a stringent FDR, a small number of well-supported genes were identified in this study, however this would undoubtedly exclude a number of genuinely differentially expressed genes, some of which were previously identified in other studies as being differentially expressed.
Such statistically based M*s could reflect levels of effect that are larger than minimally adverse levels, and this can be regarded as an additional source of uncertainty or addressed by setting a more stringent protection goal in terms of incidence.
We then iteratively consider subsets of these TARs by setting an increasingly stringent rank score cutoff.
To sort through the proteins with altered SILAC ratios, we set a stringent threshold by considering only those with a calculated significance of <0.01 (Table 1 and Supplementary Material, Tables S1 S4).
These parameters set a stringent threshold and defined 12 clusters of co-expressed genes.
In this study, we set a stringent threshold for female alignments of 30.
Finally, the timing of decision-making about second children has not been studied in this population, and we did not want to artificially eliminate a potentially useful segment from our study by setting too stringent a time limit since the birth of the first child.
We do not believe that we have excluded a significant proportion of ALS motoneurons by setting too stringent selection criteria.
Is it possible that the authors in the present study might have excluded a significant proportion of ALS motor neurons from their study by setting too stringent criteria?
As the cut-off values increased from 5%to50%0%, the percentages of shared genes also increased, reflecting the fact that more shared genes are obtained by setting less stringent cut-offs.
