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Next, we mechanistically deconvoluted early post-transplant immunity by serial monitoring of whole blood using DNA microarrays.
Assessment of bleeding risk is routinely performed by serial monitoring of aPTT, PT/INR, Fib levels and PLT counts.
Significant improvement in the multiorgan dysfunction syndrome were observed during the first 2 days of Impella support as assessed by serial monitoring of the SOFA score (Table 2 and Fig. 2).
Very recently, Yu et al (2013) have shown by serial monitoring of CTC in patients with BC that these cells simultaneously expressed mesenchymal and epithelial markers, and that mesenchymal cells expressing known EMT regulators, including transforming growth factor- β pathway components and the FOXC1 transcription factor, were associated with disease progression.
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Increases in MR-proANP and copeptin >95th centile of normal population detected by serial monitoring during follow-up in ambulatory patients appear to be common and predictive of increased risk of short-term events including death.
Persistence or increase of bacterial loads over time by serial monitoring might indicate insufficient treatment, antibiotic resistance or insufficient focus control, while documented decreases of the bacterial load could allow discontinuation of antibiotic therapy.
Moreover, accurate documentation of tissue ischemia and perfusion recovery by means of histology requires the collection, and often the destruction of tissue samples, thereby providing limited clinical relevance and prohibiting serial monitoring of the biologic processes in living animals [26].
ctDNA shows great promise for low-invasive serial monitoring of tumour burden and heterogeneity through treatment cycles.
Serial monitoring of biventricular function enables earlier detection of recovery, which may be assessed during echocardiography by modulating the ECMO flows.
Serial monitoring of serum CEA for predicting recurrence and prognosis of CRC has been established [ 4].
The predictive value of serial monitoring of ANCA titers remains controversial [ 68– 71].
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