It is possible that hypoxia systemically augments the production of NO from dietary nitrate by sequential reduction, with the expression and nitrate reductase activity of xanthine oxidoreductase increasing under hypoxic conditions [ 39].
Thus, O2 may have been excluded from cells by reduction to extracellular O2– or, when it did enter cells, detoxified by sequential reduction of O2 to O2– and then to H2O2 and finally to water.
Lysate samples were thawed to room temperature and their concentrations equalised to 1 μg/μL (50 μL volume) with RIPA buffer, and further processed for trypsin digestion by sequential reduction of disulphide bonds with TCEP and alkylation with MMTS.
Stepwise elution, characterized by sequential reduction of the hydrophobic interactions between the protein and adsorbent, was presented as a dynamic strategy for tuning conformational transitions to favor the native conformation and reduce the formation of protein aggregates during the elution process.
Bimetallic core-shell NPs were synthesized by sequential reduction of metal ions.
Even for the case in which there are several sinusoidal waves, the spectral parameters can approximately be derived by sequential reduction.
Metabolism of arsenic proceeds through sequential reduction and oxidative methylation being mediated by the following genes: purine nucleoside phosphorylase (PNP), arsenic (+3) methyltransferase (As3MT), glutathione S-transferase omega 1 (GSTO1), and omega 2 (GSTO2).
Recent results indicate that redox processes are not completely controlled by the sequential reduction chain (that is electron acceptor availability) but that electron donor availability may be an important regulator.
However, previous studies have found that gait freezing episodes are commonly preceded by a sequential reduction in step length a deficit that would account for the increased step length variability in our PD-FOG patients (Nieuwboer et al., 2001; Chee et al., 2009).
As a consequence, the maturation of nuclear pre-60S particles is accompanied by major compositional changes that lead to a sequential reduction of complexity and to the acquisition of export competence.
