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Compounds 5a e, 6a d were prepared by sequential manipulation of 3 with α,β-unsaturated ketones.
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This work reports on a simple scheme for transport and sequential manipulation of droplets using ratchet-shaped microchannels.
The task consisted of sequential manipulation of nonmagnetic hard aluminium spheres with equal mass (32.5 g) and volume (11.5 cm3), which were presented to the subjects' right (dominant) hand by an investigator standing next to the scanner.
During the course of these studies, several papers were published investigating the effect of sequential manipulation of KP-10 on in vitro and in vivo activity (8, 22, 24, 27).
For site-specific integration in the chromosome of E. coli, we adapted a marker-less gene deletion strategy that enables sequential manipulation of multiple gene loci leaving no antibiotic resistance genes or any other vector sequences in the chromosome.
Spatial visualization involves sequential manipulations of spatial information, such as seen with a Rubik's cube or paper-folding task (Kozhevnikov, Motes, & Hegarty, 2007).
Thirty percent of patients achieved an objective response, suggesting the potential of sequential endocrine manipulation of hormone-sensitive tumor cells [ 128– 128].
This implies that sequential genetic manipulation of target genes identified through interspecies comparative microarray analysis may be an efficient and rational strategy for Streptomyces strain improvement [ 10, 37].
Titrations were performed by sequential addition of ligand to enzyme.
Sensitivity analysis was performed by sequential omission of individual studies.
This is achieved by simple manipulation of the left-hand sides of the differential equations.
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