Sentence examples for by sequence coverage and from inspiring English sources

In spite of being relatively effective, SNP identification from ESTs is limited by sequence coverage and depth.

However, these limitations can be minimized by increasing sequence coverage and by using complementary genetic analyses (e.g. array-based CNV-ascertainment).

To rule out the altercations conferred by low sequence coverage and assembly we established the complete absence of lin genes by comparing both contigs (validated by paired end criterion) and ORFs (contigs = BLASTX and ORFs = BLASTP) against the reference lin gene database [ 8].

Although the total number of sequences differed among the four sequencing experiments (see Additional file 1: Table S2), gene expression levels estimated by sequence coverage showed high positive correlation between both the biological and the technical replicates (see Additional file 1: Figure S2).

Sorting by sequence coverage showed a steep drop from full-length (~185 residues) to half-size proteins after about 4600 hits.

The assembly contained 23.06% TEs as defined by sequence coverage.

The IS elements of both plasmid and virus appeared to be stable judging by the uniform sequence coverage, and, moreover, PCR amplification of their genomic locations did not reveal any loss of the IS element.

The protein coded by orf24 of pPDL2 has 100% sequence coverage and identity with the partitioning protein ParA of plasmid pUT1 of S. japonicum UT26S.

The ratio of transitions to transversions was approximately 1.77 and likely caused by the sequencing coverage and filtering steps.

However, it should be noted that not all positions with an error prone sequence motif seems to be effected by sequencing coverage bias.

Furthermore, read counts observed at a particular transcript location are limited by the depth of sequencing coverage and are dependent on the relative abundance of other transcripts.