Sentence examples for by sequence conservation and from inspiring English sources
We propose that conservation of secondary structure of the well-conserved domains (defined by sequence conservation and the presence of highly conserved amino acids) probably reflects conservation of catalytic functions and/or protein-protein interactions of these domains.
To compare methylomes of human and mouse PGCs, we lifted over published mPGCs BS-seq data (Kobayashi et al., 2013) to the human genome by sequence conservation and compared CpG methylation at conserved repeat-free 1 kb tiles.
Despite being supported by sequence conservation and expression data, knockout homozygotes of many genes show no visible effects, at least under laboratory conditions.
Domain boundaries were defined iteratively by sequence conservation and context.
The sub-domains are determined by sequence conservation and not by their function.
In this study we show that the parasitic protist, E. histolytica, thought to be an early branching eukaryote, possesses the major classes of snoRNAs as judged by sequence conservation with yeast and human.
By analyzing sequence conservation and gene expression data, we identify nearly 400 conserved noncoding regions.
The above suggested cases of exon duplications are not supported by sequence conservation of (surrounding) exonic and unconstrained intronic sequences.
Secondary and tertiary structure models of rRNAs are also being derived from comparisons of rRNA sequences by using sequence conservation and covariation analyses, and assuming that sequence positions with similar patterns of variation across multiple organisms are base-paired in the rRNA structure [4] [7].
In this section, we will report the experiments conducted to evaluate the performance of our proposed approach, ProteRNA with the combination of SVM-based classifier with evolutionary profiles and conserved residues discovery by sequence conservation.
In this article, we proposed the prediction framework "ProteRNA" with the combination of SVM-based classifier with evolutionary profiles and conserved residues discovery by sequence conservation for identifying RNA-interacting residues in a RNA-binding protein.
