Sentence examples for by sequence complementarity to from inspiring English sources

Target specificity is directed by sequence complementarity to the microRNA - particularly in the 2'-8' seed region - and families have been identified based on miRs that have highly similar or identical seed sequences [8].

RISC is guided to the target messenger RNA (mRNA) by sequence complementarity to miRNA [ 13, 14].

There are two classes of ncRNAs: one that includes antisense RNA and microRNA, and functions by sequence complementarity to target mRNA or DNA, whereas another functions independently of sequence complementarity by forming a functional 3D structure to target protein or macromolecules as an apparent equivalent to a protein.

This is achieved through binding of sRNAs by partial nucleotide sequence complementarity to their target mRNA sequences.

In the scenario I, the regulation is mediated by the mRNA-sRNA interaction, in which the sRNA acts as a fine-tuner of gene regulation through binding of the sRNA by partial nucleotide sequence complementarity to its target mRNA sequences.

This is achieved through binding of miRNA by partial nucleotide sequence complementarity to the target mRNA sequences that helps the miRNA:mRNA duplex to be part of the multi-protein silencing or RISC RNAA induced silencing complex).

Mature miRNAs of 18 22 nt in length are cleaved by the ribonuclease III family member Dicer from 60 90 nt hairpin-loop precursors (pre-miRNAs), and act to repress translation by binding with partial sequence complementarity to the 3'-UTRs of their target mRNAs.

miRNA target candidates identified by microarray were examined for sequence complementarity to the seed region of the miRNA.

Target prediction by TargetScan database is established on sequence complementarity to target sites with emphasis on perfect base-pairing in the seed region and on sequence conservation among species [88].

To decrease the possibility of off-target silencing, both 19 nt siRNA sequences were analyzed by BLAST search to ensure a lack of significant sequence complementarity to any known chicken gene sequence.

Each CRISPR area contains a predicted tracrRNA sequence, with partial sequence complementarity to the CRISPR repeat, preceded by a σ -10 sequence (gnTAnAAT), located downstream of the CRISPR repeats.