Sentence examples for by sequence complementarity and from inspiring English sources
The Cas9 proteins are type II CRISPR-associated, RNA-guided DNA endonucleases that identify double-stranded DNA targets by sequence complementarity and protospacer adjacent motif (PAM) recognition.
Roles of sRNAs were predicted by sequence complementarity and our results showed that many sRNAs identified in this work might be directed against various transcription factors.
Integration of gene and miRNA profiling was performed by both sequence complementarity and expression correlation.
There are two classes of ncRNAs: one that includes antisense RNA and microRNA, and functions by sequence complementarity to target mRNA or DNA, whereas another functions independently of sequence complementarity by forming a functional 3D structure to target protein or macromolecules as an apparent equivalent to a protein.
Target mRNA specification is determined by sequence complementarity between the seed sequence of an individual miRNA and the target mRNAs (Baek et al, 2008; Eulalio et al, 2008; Selbach et al, 2008; Bartel, 2009).
Target specificity is directed by sequence complementarity to the microRNA - particularly in the 2'-8' seed region - and families have been identified based on miRs that have highly similar or identical seed sequences [8].
In the most ideal situation where hybridization is determined solely by sequence complementarity, a designed probe would either consistently hybridize if the assumed target orientation is correct or not hybridize at all if wrong.
MicroRNAs are small RNA molecules that regulate gene expression by targeting gene transcripts by sequence complementarity.
RISC is guided to the target messenger RNA (mRNA) by sequence complementarity to miRNA [ 13, 14].
Metacore pathway analysis predicted multiple targets of miR-206, including KLF4, which was further supported by sequence complementarity alignment.
Dicer (Dcr1) cleaves these dsRNA molecules into short interfering RNAs (siRNAs) that guide the Argonaute (Ago1 -containing RITS effector complex to homologous nAgo1 -containingts by sequence complementaRITS.
