Sentence examples for by sequence alignment and from inspiring English sources

The protein sequence similarity between two targets is calculated by sequence alignment and is defined as S t seq (t u, t v ) = align (t u, t v ) / align (t u, t u ) align (t v, t v ), where align(t u, t v ) is the Smith-Waterman alignment score [ 15] between t u and t v.

In this study, we characterized the genetic relatedness of human noroviruses in the context of their host carbohydrate-binding specificity by sequence alignment and structural analysis, followed by site-directed mutagenesis and functional assay for strains representing both GI and GII and both A/B and Lewis binding groups.

Results from functional analyses of variants are largely supported by sequence alignment and protein modelling predictions.

SNPs were identified by sequence alignment and visual examination of the sequence trace files for overlapping base-calling peaks.

Five conserved domains were identified by sequence alignment, and their positions in the protein sequences were determined (Table  3).

Table 2 lists five conserved motifs that were identified by sequence alignment, and their positions in the protein sequences.

Specifically, the integration of stress-responsive cis-motif annotation and comparative sequence analyses, which were carried out and described previously by sequence alignments and phylogenetic relationship studies, has been shown to effectively aid in the prediction of stress-related TCS members.

These data support the idea that the C2 domain is also present in Dll-1, as suggested by sequence alignments, and binds Ca2+ despite the high level of sequence variation in the putative calcium-binding loops, which makes it difficult to predict which residues are likely to coordinate the metal ion.

Target similarity has been assessed at the level of protein sequence, with the degree of conservation of specific drug targets in humans and model organisms evaluated by performing sequence-by-sequence alignments, and limited studies have been conducted on the domain conservation for the androgen receptor (AR) and estrogen receptor α (ERα).

Because false positive SNPs could be introduced by sequence alignment errors and sequencing errors, only the SNPs that were present in more than one EST were used to detect allele-specific transcript structure variation in this paper.

The relationship between contigs was displayed using ContigScape [ 84], determined by sequence alignment analysis and verified by PCR.