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This hypothesis is substantiated by secondary analyses of a preventive trial in top level volleyball athletes.
This notion was recently confirmed by secondary analyses of several major prospective interventional studies in diabetes, originally aimed at assessing the benefits of glycemic control (8– 11).
Groups at high risk of loneliness were identified by secondary analyses of the Elderly Health Survey 2005 of the community health service [ 7], e.g. elderly persons with physical limitations, a low income, and mild mental disabilities, and recently widowed persons.
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This primary intention to treat analysis will be supplemented by secondary analyses that take account of eradication treatment compliance, whether aspirin is continued and whether a PPI is started.
We also explored the effects of potential herd immunity, serotype replacement, and vaccine efficacy waning by conducting secondary analyses of different scenarios.
These analyses will be implemented in a set of primary analyses, arising from the original report of a GxE interaction involving 5-HTTLPR variation, and supplemented by secondary analyses intended to aid in the interpretation of the main findings and to address numerous issues related to possible heterogeneity between the contributing studies.
The BARO was developed using risk factors well known from the literature and by means of secondary analyses of data from a psychiatric prevalence study in adjudicated adolescents [ 11].
This work was supported by a grant from Pfizer for secondary analyses of CARDS data.
16 Secondary analyses of the study by Inouye et al suggested that patient mobilisation and orientation might have been most influential in reducing delirium arising in hospital.
We also conducted planned secondary analyses of whether effect modification was mediated by digoxin dose or by serum digoxin concentration.
The largest study was by Black et al. [7], who performed secondary analyses of three large randomised controlled trials of bisphosphonates.
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