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The information on cancer-related gene mutations was obtained by screening the database Cosmic [ 37].
The structural characterization of protein motifs and domains was performed by screening the database ExPASy [ 57].
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The EF is the proportion of true positives (the actives) in the set of compounds retrieved over the proportion of true positives that would be obtained by screening the whole database [5].
The level of evidence is determined by screening the electronic database PubMed.
The level of scientific evidence is determined by screening the electronic database PubMed.
CCL20 (macrophage inflammatory protein-3α) is a recently described C-C chemokine identified by screening the GenBank database for expressed sequence tags for novel chemokine molecules.
Genes, whose promoter has been described in literature as being methylated in certain cancer types selected by screening the PubMeth database.
In this study, PKS genes were identified by screening the PKS sequence database, especially the domain database, which include: ketoacyl synthase (KS), acyl transferase (AT), ketoreductase (KR), dehydratase (DH), enoyl reductase (ER), and acyl carrier protein (ACP, also known as PP domain).
Nine of the eleven MBD-containing protein sequences could also be detected by screening the Sequence Similarity DataBase (SSDB) [ 25] at GenomeNet.
PDE4-inhibitory activity has not previously been attributed to moexipril, but we identified the compound as a candidate PDE4 inhibitor by screening the MDDR drug database using the chemoinformatics SEA method.
To supplement the PCR-based Psg expression studies, we performed 'virtual northern' analysis in silico by screening the public EST database for sequences matching Psg N1 or A-domains and counting the numbers of matches (Fig. 5).
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