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The elasticity drop may be understood by screening of the ionic interaction between constituents in HA upon Ta incorporation.
V209A variant enzyme was selected with the highest activity by screening of mutant library produced from error-prone PCR.
High 3-HP yield was achieved by screening of active aldehyde dehydrogenases and by minimizing byproduct synthesis (gapAA1GΔldhAΔpta-ackAΔpoxBΔglpK).
Traditionally, novel compounds with antiprotozoan activities have been identified by screening of compound libraries in high-throughput systems.
The suitability of this assay system in drug discovery was demonstrated by screening of 3388 small molecule compounds.
Here, we report the identification and characterization of CV-N-binding peptides, which were isolated by screening of M13 phage-displayed peptide libraries.
Geraniol production varied from trace amount to 43.19 mg/L (CrGES, GES from Catharanthus roseus) by screening of nine GESs from diverse species.
Small molecules potentially mimicking the hormone erythropoietin have been discovered by screening of a library of rationally designed multicomponent reaction molecules in a functional cell-based assay.
Alternatively, novel restriction site changes can be inserted into a gene followed by screening of individual plaques for the novel change.
To increase the astaxanthin content in X. dendrorhous, cultivation protocols have been optimized and astaxanthin-hyperproducing mutants have been obtained by screening of classically mutagenized X. dendrorhous strains.
The technology was demonstrated by screening of a selected 23-compound fragment collection of documented binders, mostly amidines, using trypsin and thrombin as model target protease proteins.
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