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Several studies have shown that the degree of impaired respiratory function can be assessed by respiratory function testing [ 5- 7].
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However, most research to date has focused on disease modification measured by respiratory function tests, with limited objective information on the wider impact of IPF on daily life.
Parents were usually present during the respiratory function testing.
A physical assessment by a trained nurse included electrocardiograph, blood pressure, hearing and vision, anthropometric measures, respiratory function testing and blood samples.
By school-age, children are able to co-operate with standard respiratory function measures, but again respiratory function testing is mostly a research tool, in the absence of respiratory symptoms or signs.
Although the breathing pattern is affected by both the neural control of breathing and respiratory mechanics, TB-measurements can be used as a first-line tool in the respiratory function testing of infants after neonatal intensive care.
Secondary outcome measures were respiratory function testing and, hematological examinations, and sputum cell count.
Safety and adverse events were assessed by reported signs and symptoms, physical examinations, blood tests, cardiac and respiratory function tests.
The respiratory function tests and transthoracic echocardiogram will be performed by routine clinical personnel at the treating hospital and they will be unaware of the group allocation.
A respiratory function test was performed at the 15-year assessment by a research nurse using a portable spirometer (Micro Medical GP MS07).
In her previous examinations, fiberoptic bronchoscopy, thorax computed tomography and respiratory function tests were applied, and these tests were evaluated as normal by the pulmonologist, but her PTH level, thyroid function tests and calcium level had not been checked yet.
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