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By repressing the feedback inhibition of glucosamine-6-phosphate synthase, increasing the accumulation of N-acetylglucosamine and pyruvate, and blocking the catabolism of NeuAc, the NeuAc yield reached 7.85 g/L in fed-batch fermentation [47].
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Snf1 affects HXT expression via repression of Mig1,2, which in turn plays additional roles in glucose positive and negative feedback loops by repressing the STD1, MTH1, SNF3, and HXT genes (Kaniak et al., 2004).
The CLV3 gene encodes a 96-AA secretory protein that functions in a feedback regulation loop to restrict the number of stem cells in SAMs by repressing the expression of the WUSCHEL (WUS) transcription factor [ 16, 21].
They all did this by repressing the E-cadherin promoter.
This indicates that sporulation efficiency can be improved by repressing negative feedback from Ime2 to Ime1.
The mTORC1 inhibition induced by these drugs fails to repress the negative feedback loop that results in phosphorylation and activation of AKT, and it is unable to block the mTORC2 positive feedback to AKT [ 37].
The peak expression of CRY1a was incremented in cry1a- plants (Figure 6A); this could be the effect of an auto-regulatory feedback mechanism mediated by CRY1a and repressing the transcription of its own gene.
These bound TFs can then promote or repress transcription by stimulating or repressing the assembly of preinitiation complexes.
The binding of the transcription factor to the site repressing the transcription of CI (negative feedback) is denoted by D− CI2.
43, 79 87] has been realised, including feedback by repressing proteins with given trigger regime of gene functioning.
AHRR is a feedback modulator by repressing AhR-dependent gene expression and is involved in the regulation of cell growth and differentiation [ 25].
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