Sentence examples for by repressing gene expression from inspiring English sources
Since miRNAs act by repressing gene expression, those targeting MRF would show inverse expression to the above trend.
Fur is conserved in a wide variety of bacterial species and functions similarly in all of them by repressing gene expression under conditions of sufficient cellular iron.
miRNAs play critical roles in many biological processes by repressing gene expression at the post-transcriptional level through binding usually at the 3'-untranslated region of the target mRNA [3], [4].
The leukaemic fusion protein RUNX1-CBFA2T1 inhaematopoeticopoetic differentiation by repressing gene expression via recruitment of histone deacetylases [ 4- 7], and by sequestering transcription factors such as C/EBPα, SMADs or vitamin D3 receptor [ 8- 11].
MicroRNAs (miRNAs) are a broad class of small non-coding RNAs that act mainly by repressing gene expression through interactions with complementary sequences in coding and non-coding regions of mRNA targets [ 1].
Another gene up -regulated in mid - to late embryogenesis (cluster 1) was a homolog of CLF, a member of the polycomb -group (Pc -G) proteins, which regulate many developmental processes in plants and animals by repressing gene expression in a cell -specific manner via trimethylation of histone H3 lysine 27 (H3K27me3) [ 43].
CtrA controls various functions during cell cycle progression by activating or repressing gene expression.
E2F is a family of transcription factors regulating cell proliferation by activating or repressing gene expression during G1/S phase transition.
For example, proteins that bind to specific regions of DNA act as transcription factors by activating or repressing gene expression of the DNA.
However, post-transcriptionally repressing gene expression by binding to 3'UTRs is still the mainstream regulative mode of miRNAs and the complexity of this mode is gradually emerging.
It is posited that this bivalent status may be integral to pluripotency by providing a mechanism for repressing gene expression without permanent silencing.
