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Thereby, this microRNA would control the amount of nuclei within each myotube by repressing expression of collagen XXV.
BMP signaling interferes with FGF-dependent signaling, at least in part by repressing expression of its receptor FGFR170.
It is plausible that the mutation in SMG11/D2 might decrease BR signaling or responses by repressing expression of BR signaling genes (e.g. OsBRI1 and BU1), resulting in small grains.
In amphioxus, AmphiHox1 has been shown to mediate the effects of RA signaling by repressing expression of pharyngeal markers in the posterior foregut/midgut endoderm [62].
Overall, our studies demonstrate that Hr evokes an anti-apoptotic response by repressing expression of p53 and pro-apoptotic events regulated by p53.
By repressing expression of the genes encoding these CDK inhibitors, c-Myc eliminates two major obstacles to cycle progression.
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In addition, MYC2 has been shown to be necessary for the jasmonate-mediated repression of root growth by directly repressing expression of PLT1 and PLT2[ 71].
The transcriptional regulator Hmga2 is normally expressed in neural stem cells early in embryonic development, where it actively drives self-renewal by indirectly repressing expression of negative regulators of cell cycle progression [43].
TGFβ1 reduces autophagy, in part, by selectively repressing expression of autophagy mediators in normal lung fibroblasts.
Others have provided evidence for the role of the ZEB proteins during the induction of EMT by their repressing expression of E-cadherin and other epithelial structural components necessary for epithelial phenotype [ 44, 50, 51].
Once this differentiation driving transcription network is activated we suggest KLF3, KLF5 and KLF9 can accelerate loss of the stem cell state by directly repressing expression of the Klf2 and Klf4 genes themselves.
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