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Thus, in addition to its sleep-promoting role reported previously, SSS may also promote wake by repressing activity of nAChRs.
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Multiple male-determiners (>4) in M. domestica and M. scalaris populations could reflect the increased mutation rate by which new repressing activities of tra genes can evolve from the entire gene repertoire of the genome.
Our results indicate that Amotl2a limits the number of cells and thus the size of the migrating pLLP by repressing the activity of both Lef1 and Yap1.
The Hox genes achieve this by repressing the activity of a signaling pathway called Wnt so that Wnt activity in the tail-bud progressively decreases as the embryo develops.
miR-1 and miR-133 modulate skeletal-muscle-cell proliferation and differentiation by repressing the activity of HDAC4 (histone deacetylase 4; a signal-dependent inhibitor of muscle differentiation) and SRF, respectively, thereby establishing negative-feedback loops for muscle-cell differentiation [ 23].
These results suggest that plant aquaporins could be involved in salt tolerant mechanisms by repressing the activity of water channels under salinity stress.
Wg counteracts this spreading by repressing the activity of the Notch receptor.
SIRT4 has been shown to regulate insulin secretion by repressing the activity of GDH (6).
These findings indicated that OA inhibited glycolysis by repressing the activity of HIF1 α.
Thus, we concluded that miR-133 functioned in myoblasts by repressing the activity of the ERK1/2 pathway through targeting FGFR1.
Next, miR-133 represses myoblast proliferation and promotes cell differentiation by repressing the activity of the ERK1/2 pathway through targeting FGFR1 and PP2AC.
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