Sentence examples for by replacing the null from inspiring English sources

Null alleles are simulated in heterozygote genotypes by replacing the null allele with the other allele (a i. a n becomes a i. a i ).

This is done by replacing the null hypothesis of complete spatial randomness, with a null hypothesis that accounts for each individual's probability of being a case based on his/her known risk factors and covariates.

The LRT statistic is then defined as the ratio of the null and alternative likelihoods obtained by replacing the unknown parameters with their null and alternative maximum likelihood estimates.

To investigate this possibility, we reanalyzed the data by replacing the parametric distribution implementing the null hypothesis in the original UE analysis by a distribution derived from surrogates.

To investigate an enhanced or specialized role for rab7 in the nervous system, we generated a null mutant by replacing the rab7 open reading frame with a Gal4 knock-in cassette; the Gal4 knock-in provides a means to express any gene of interest under the endogenous regulatory elements of rab7 in either heterozygous or homozygous rab7 mutants (Brand and Perrimon, 1993; Chan et al., 2011, 2012).

Using one of these sltBΔ::riboB Af transformants (MAD3669), we generated by transformation a null sltA allele by replacing the sltA coding region with pyrG Af, as above.

To investigate whether HEL67 protein has a role in asrRNA fragmentation, we generated a L. infantum null HEL67 mutant by replacing the HEL67 gene by two different selection marker genes.

Firstly we generated a new null sltB mutant by replacing the sltB coding sequence with the riboB gene from A. fumigatus (riboB Af) and using strain MAD1427 as recipient.

Enamelin null mice were generated by replacing the Enam coding sequence from the translation initiation site through exon 7 with a lacZ reporter gene [ 19].

The expansion is accomplished by replacing the 1's in with permutations or circulants, and the 0's with null subblocks.

Lrp4 null mice were generated as described in Figure 1 by replacing the first exon with a neomycin resistance cassette.