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It will be interesting to determine whether Plk1 is controlling contractile ring formation by regulating the interactions or activities of Rho-GAP and Rho-GEF in vertebrate cells.
Some of these genes function by regulating the interactions and coordinations between different cell types within maternal-zygotic interfaces in the seed, but the relative contributions of the maternal and zygotic genomes and the nature of how these two types of genomes communicate to coordinate seed growth are poorly understood.
Because SUMOylation can act by regulating the interactions of the substrate protein with other macromolecules, such information is useful.
This involves the enhancement of the innate and the inhibition of the adaptive immune system by regulating the interactions between lymphocytes and antigen presenting cells.
Members of these chaperone families have been shown to be involved in PB/SG assembly by regulating the interactions between Q/N domain proteins and prion proteins (Gilks et al. 2004; Rikhvanov et al. 2007; Matsumoto et al. 2011; Nadler-Holly et al. 2012).
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These results indicate that the JNK pathway has a critical role in the survival of neurocytes by regulating the interaction between BAD and 14-3-3 14-3-3 14-3-3
Previously, phosphorylation of the RLC has been hypothesized to be important for this role by regulating the interaction of the RLC with anillin, a protein that binds F-actin, membranes, and phospho-RLC myosin II [28].
It can promote cell motility by regulating the interaction between vitronectin and uPA [ 37].
These results suggest that ULK3 phosphorylation of IST1 may delay abscission by regulating the interaction of IST1 with late-acting components of the ESCRT machinery.
Rather, TORC1 controls RP gene expression in part by regulating the interaction between Fhl1 and Ifhl via the forkhead-associated (FHA) domain of Fhl1 (Schawalder et al. 2004; Wade et al. 2004; Rudra et al. 2005).
Polo/Plk1 seems to play a crucial part in resetting the reduplication license at old centrioles through the regulation of centriole disengagement [ 37]; perhaps it also has an important role in the primary licensing of new centrioles by regulating the interaction between DSas-4 and Asl.
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