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Slow-acting neurotransmitters control the efficacy of fast synaptic transmission by regulating the efficiency of neurotransmitter release from presynaptic terminals and by regulating the efficiency with which fast-acting neurotransmitters produce their effects on postsynaptic receptors.
CREB controls the efficacy of synaptic transmission by regulating the efficiency of neurotransmitter release from presynaptic terminals [3], [4].
Recent studies in Saccharomyces cerevisiae, for example, have revealed mechanisms that modulate the synthesis of C-terminally extended proteins by regulating the efficiency of stop codon readthrough in response to cellular stress, a process that may impact on the ability of cells to respond and adapt to fluctuating environmental conditions (reviewed in [12]).
These results support the idea that epigenetic factors may directly contribute to genomic instability and aging by regulating the efficiency of DSB repair.
For example, the phosphatidylethanolamine N-methyltransferase (PEMT) and betaine-homocysteine methyltransferase (BHMT) may influence As metabolism either by regulating the efficiency of the one carbon metabolism or by direct methylation of As.
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The miRNAs play a role in gene silencing by regulating the stability or translational efficiency of target messenger RNA (mRNA).
They play important roles in cancer pathogenesis, including disease onset, progression, and metastasis, by regulating the stability and translation efficiency of their target mRNAs.
Thus, these RanGTP-binding proteins would allow greater NES variability and potentially regulate the efficiency by which specific NESs are recognized by Crm1.
Thus, structural transitions controlled by changes in the degree of flexibility of linkers connecting consecutive cohesin modules could regulate the efficiency of substrate recognition and hydrolysis.
In addition, our data suggest that the dose of BMP4 regulates the efficiency of PGC specification.
In addition to processes that may increase or decrease Aβ production by regulating secretase efficiency or transcription, the presence of a β-secretase in the gene repertoire is an important consideration.
More suggestions(16)
by regulating the cohesion
by regulating the metabolism
by regulating the bias
by recognizing the efficiency
by regulating the filter
by regulating the number
by comparing the efficiency
by regulating the blend
by regulating the function
by regulating the use
by regulating the chromatin
by regulating the rotation
by regulating the balance
by regulating the activity
by testing the efficiency
by regulating the development
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