Sentence examples for by regulating the differentiation from inspiring English sources

Recent advances in regenerative medicine allow us to replace and repair organs or structures by regulating the differentiation of undifferentiated MSCs.

The interferon response gene IRF1 may act as a tumor suppressor by regulating the differentiation and proliferation of myeloid cells via the Stat pathway [63] [66].

IFN-α/β has profound effects on immune cell development [ 41] by regulating the differentiation of B and T cells, myeloid DCs and natural killer cells.

FASLG contributes to neuronal cell loss by regulating the differentiation and function of peripheral myeloid cells, rather than via direct FAS-induced apoptosis in FAS-bearing neural cells [ 31].

The Notch pathway has a vital role in normal colon homeostasis by maintaining stem/progenitor cells and by regulating the differentiation of goblet cells (Fre et al, 2005; Radtke et al, 2006).

Dll4 is primarily expressed in endothelial cells and acts specifically by regulating the differentiation and activity of tip cells present at the growing front of new vessels (26– 26).

In conclusion, estrogen inhibits osteoclast formation by regulating the cell differentiation, apoptosis, adhesion, and other pathways.

Because early (E12.5) IPC number was normal in Sall1-deficient animals, these observations support the hypothesis that Sall1 might influence the transition from deep to superficial neuronal specification by regulating the terminal differentiation of IPCs.

30 Another mechanism by which obesity can affect bone metabolism is through receptor activator of NF-κB (RANK), RANK ligand (RANK-L), and osteoprotegerin (OPG), by which osteoblasts are capable of regulating the differentiation and activity of osteoclasts.

For example, in Arabidopsis, bHLH genes have been shown to be involved in regulating the differentiation of trichomes [ 58], and a bHLH transcription factor, UPBEAT1 (UPB1), modulates the balance between cell proliferation and differentiation by directly regulating the expression of a set of peroxidases in the root [ 59].

Wnt ligands have been suggested to operate by regulating the proliferation and differentiation of lobuloalveolar progenitor cells during pregnancy.