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Zhu, Z. & Bhat, K. M. The Drosophila Hem/Kette/Nap1 protein regulates asymmetric division of neural precursor cells by regulating localization of Inscuteable and Numb.
Here, we report on a novel role for gyc76C in salivary gland invagination, migration and lumen shape, in part by regulating localization of the laminin matrix and talin.
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Additional control is exerted by activin receptor interacting proteins (ARIPS) which regulate localization of activin receptors and positively or negatively regulate activin signalling [ 23].
Additionally, the Hem/Kette/Nap1 protein has been shown to play a very important role in the asymmetric division of Drosophila neuroblasts; it does so by regulating the localization of Numb and another adaptor protein known as Inscuteable [ 38].
Drosophila Abelson tyrosine kinase (Abl) regulates epithelial morphogenesis, at least in part by regulating the localization of Enabled [3, 18].
Nutrients influence Pol I activity by regulating the localization of two Fhl1-binding cofactors, the activator Ifh1 and the repressor, Crf1 (Martin et al., 2004).
The INO80, SWR, and NuA4 complexes all share a common influence on chromatin composition by regulating the localization of histone H2A.Z-containing nucleosomes (Htz1p in yeast).
These data indicate that PGE2 may act to attenuate cytokine-induced inflammatory responses in RA synovial fibroblasts by regulating the localization of specific NF-κB family dimers [ 27].
Our studies suggest that gyc76C controls salivary gland invagination, collective migration and lumen shape, in part by regulating the localization of talin and the laminin matrix.
In the follicular epithelium of the Drosophila ovary, Tsp66E, the Drosophila orthologs of vertebrate KAI1/CD82, localizes to junctions near the basal surface where it affects actin polarity by regulating the localization of αPS2 integrin (Han et al., 2012).
(R -PFI-2, a potent and selective inhibitoR -PFI-2D7 [ 102], was developed fR -PFI-2arly hit from high-throughpotentreening, and waselectiveo affect the Hinhibitorway by regulating the lofalization of YAP from the cytoSETD7o the nucleus.
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