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This suggests that MR-1 may play a role in cancer progression by regulating cell adhesion and motility.
Notably, this gene plays a central role in heart morphogenesis and angiogenesis by regulating cell adhesion and cell migration.
These observations indicate that the lack of DGAT1 might reduce leukocyte infiltration by regulating cell adhesion and transendothelial cell migration.
Increasing evidence is emerging highlighting the role of parathyroid hormone-related protein (PTHrP) during metastasis by regulating cell adhesion.
In human umbilical vein endothelial cells (HUVECs), Ezh2 also promotes angiogenesis by regulating cell adhesion and communication (Dreger et al., 2012).
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To elucidate the mechanisms by which Pttg2 regulates cell adhesion, we analyzed the gene expression profiles of cells depleted of Pttg2 compared with wild-type cells.
Further investigation of CD22-Lyn-Syk interactions could lead to a better understanding of the precise mechanisms by which CD22 regulates cell adhesion and migration pathways in B cells.
Whilst the best understood means by which snail genes regulate cell adhesion is by acting as repressors of E-cadherin expression [ 36, 38, 39], in human epidermal keratinocytes the snail-related gene Slug (Snail2) is a repressor of α3, β1 and β4 integrin expression, leading to decreased cell-adhesion to fibronectin and laminin 5 [ 40].
Consistent with this, it was shown by others that RACK1 regulates cell adhesion [ 42], moreover, silencing of RACK1 inhibited cell proliferation and decreased migration and adhesion capability of carcinoma cells [ 43].
RPTPμ not only forms an adhesive contact itself, but it also regulates cell adhesion by dephosphorylating components of the cadherin catenin complexes.
SPARC (Secreted Protein Acidic and Rich in Cysteines) has been associated with a family of non-structurally related proteins like Tenascin and Thrombospondin that regulate cell adhesion by inducing focal cell contacts disassembly [12].
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by reducing cell adhesion
by downregulating cell adhesion
by regulating cell maturation
by analyzing cell adhesion
by inducing cell adhesion
by targeting cell adhesion
by supporting cell adhesion
by regulating cell type
by modulating cell adhesion
by regulating cell migration
by expressing cell adhesion
by regulating leukocyte adhesion
by regulating cell self-renewal
by confining cell adhesion
by controlling cell adhesion
by regulating cell cell
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