Sentence examples for by reduction in expression from inspiring English sources

In the case of Plxdc2, misexpression of the gene in the chick was not accompanied by reduction in expression of Cash1, but by increased Cash1 levels and a dorsal-ventral expansion of Cash1 expression 24 hours following electroporation.

Moreover, our data suggest that inhibiting the IGF-1R pathway suppresses HR by reduction in expression of RAD51.

We have presented evidence here that this phenotype is accompanied by reduction in expression, from symptom onset, of the cholesterol synthesis pathway, and genes involved in nervous system development, including axonogenesis, synapse formation, growth factor signalling pathways, cell adhesion and microtubule-based processes.

This impairment is characterized by reduction in CD44 expression, IFN-γ production, proliferation and cytotoxicity.

Abnormal calcium handling in the early stages of SCA2 pathogenesis may be further aggravated by reduction in Calb1 expression and calbindin-28K protein levels.

Our finding that endocytosis and autophagy are inhibited in cells depleted of C9ORF72 therefore identifies cellular processes affected by reduction in C9ORF72 expression.

The initial suppressive effect of HBO was more pronounced on mononuclear osteoclast formation than on multinuclear osteoclast formation, and this was accompanied by reduction in the expression of key regulators of osteoclast formation, RANK and Dc-STAMP.

Repression of Pxn transcription was accompanied by slight reduction in expression of Croquemort (Crq) and Hemolectin (Hml), while transcript levels of eater were essentially unchanged (Fig. 3B).

The direction and magnitude of fold changes in expression were dominated by a reduction in expression for 7732 probe sets compared to 2251 probe sets increasing (Fig.  2).

This effect was accompanied by a reduction in expression of cyclin D1 and cyclin dependent kinase 4 (CDK4), and an increased expression of p27.

Interestingly, JMJD1A or JMJD2C depletion leads to ES cell differentiation and is accompanied by a reduction in expression of pluripotency genes, favoring induction of lineage marker genes.