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Thus, in worms, reduced activity of the insulin-signalling pathway may exert a very general beneficial effect on the cellular environment during aging, by reducing the propensity of aggregation-prone proteins to form aggregates. Understanding exactly how this occurs is an interesting future challenge.
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For example, certain nucleotide modifications are suggested to exert stabilizing effects by restricting conformational flexibility, thus reducing the propensity for enzymatic or base-catalyzed degradation.
Phosphorylation at T144/T150 in the F1 loop could disrupt membrane association either by reducing the overall positive charge in the loop, or by decreasing the propensity of the loop to form a helix.
He began by reducing the work force.
By reducing the.
The mechanism by which such crossover-interference is communicated along the chromosome is not known, but one model suggests that mechanical compression stress associated with twisting of the chromatid promotes crossovers and that the release of this stress by a designated crossover reduces the propensity for crossover nearby [ 61].
All the leading heads of state, intellectuals, artists, and scholars have been convinced for some time now that only a slender allegiance by all states to a superior governing body could relieve current economic difficulties, reduce the propensity for war and eliminate anxieties aroused by the threat of conflict, which are themselves one of the primary causes of the economic crisis.
Being a male headed household reduces the propensity to adopt improved pigeonpea varieties by about 28%%.
By using your first, middle and last name, you can reduce the propensity for errors.
As predicted by the Paircoil2 algorithm, the proline substitution of L189 strongly reduces the propensity for coiled-coil formation.
He had wanted to make design changes, he said, "to reduce the propensity for rollover" because it "was a safety factor".
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CEO of Professional Science Editing for Scientists @ prosciediting.com