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FPPa-OmoMYC acts by reducing the binding between MYC and MAX thus interfering with the transcriptional activity of MYC.
This is explained by reducing the binding affinity between the siRNA strands to the complex, thereby enabling siRNA release after cellular internalization.
The density functional theory (DFT) calculations reveal that the Fe-doping effectively decreases the energy barrier of OER path by reducing the binding of the oxygen-containing species on the surface of NiPS3.
Thus, the natural mdx mutation could impair splicing efficiency by reducing the binding of a 40 kDa SR protein to exon 23 ESE.
The calcein release assay and BODIPY diffusion from tethered LUVs reveals that Eu3+-complexed LUVs resist Aβ42-induced permeation by reducing the binding of Aβ42.
By reducing the binding of HDAC1 to other NuRD components, overexpressed APPL1 may reduce the enzymatic activity of HDAC1 and/or affect its potential to be recruited to DNA.
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The release of bFGF from the surfaces was induced by reducing the affinity binding between bFGF and immobilized-heparin due to increasing the mobility of the swollen grafted P IPAAm-co-CIPAAm) chains.
The effect of receptor antibody was included by reducing the receptor binding rate.
Therefore, this effect cannot be explained by reducing the unproductive binding of cellulases to lignin.
Surfactants may also improve the cell viability by reducing the unproductive binding of cells to fermentation residues.
Given that the concentration threshold for single-molecule imaging is ∼100 nM under conventional TIR excitation, our PMAP/TiO2/quartz surface is expected to provide a higher signal-to-noise ratio and allow the detection of weak protein protein interactions by reducing the nonspecific binding of biomacromolecules to substrates.
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CEO of Professional Science Editing for Scientists @ prosciediting.com