Sentence examples for by reducing release of from inspiring English sources

Selective estrogen receptor modulators (SERMs), similar to estrogens, possess vasoprotective effects by reducing release of reactive oxygen species.

Depression and anxiety has been linked with increased rates of recurrent chest pain, either through increased somatization or by reducing release of nitric oxide and potential decrease in endothelial reactivity [ 29, 30].

Taken together, FXR ligands counteract hepatic inflammation at several levels: directly via interaction with inflammatory pathways in hepatocytes as well as in non-parenchymal hepatic cells and by reducing release of inflammatory mediators from the intestine via a decrease in intestinal permeability and bacterial translocation.

Furthermore, we evaluated the role of extracellular HSP70 in H. pylori-infected AGS cells, and demonstrated that extracellular HSP70 protein could partial compensate for the decreased intracellular HSP70 by reducing release of cytochrome c and AIF, which could block apoptosis in gastric cells with H. pylori infection.

This reduction in necrosis was corroborated by significantly reduced release of markers of myocardial injury including creatine kinase and cardiac troponin I.

Fortunately, recent data suggested that MSCs antagonized the activation of mast cells by secreting PGE2 and TGF- β1, leading to decreased degranulation, reduced ability of chemotaxis and reduced release of TNF- α by mast cells.

In general, the polymeric matrix (PCL-pluronic) has shown to be a controlled release system very efficient for release of drugs, and in this particular composition (NREP A4), the polymeric system served as a delayed release system by reducing the release of flavonoids present in the propolis extract against L. braziliensis.

Sustained-release dosage forms are systems that elongate the duration of the action by reducing the release of the drug and its pharmacological action.

Overexpression of wild type PINK1 in SH-SY5Y cells attenuated neuronal apoptosis by reducing the release of cytochrome c and subsequent activation of caspases under basal and apoptotic stress conditions.

The hypothesis that meningeal neurogenic plasma protein extravasation could be responsible for the migraine attack [70], was strengthened by the ability of triptans to inhibit this type of inflammatory response in rodents, probably by reducing the release of SP/NKA [71].

First, and most probable, the decrease in osteoclastic bone resorption makes the skeleton a less hospitable environment for the tumor cells, by reducing the release of bone-derived growth factors that may stimulate tumor growth or production of osteolytic factors.