Sentence examples for by reducing expression of from inspiring English sources

In vitro work has also demonstrated an inhibitory effect of LGH447 on OCs, inhibiting their formation via reduced expression of phospho-ERK1/2 and NFATc1, and inhibiting resorptive function by reducing expression of matrix metalloproteinase, carbonic anhydrase II and the F actin ring necessary for functionality.

Duplicated genes are primarily maintained in mammalian genomes by reducing expression of one copy.

With regard to NTC, activation of CB receptors may influence trigeminovascular neuronal firing by reducing expression of Fos protein, as suggested by our previous study [16].

The hypothesis, that luteolin controls inflammation by reducing expression of certain cytokines (cellular biochemicals) and requires further proof.

FLC inhibits the floral transition partly by reducing expression of a key flowering-time integrator, FT [28].

Recently, it was reported that over-activation of TGF-β signaling may enhance alcohol-mediated liver damage by reducing expression of alcohol dehydrogenase 1 (ADH1) [24].

In a previous study, an En/ Spm-like transposon (Ttf1) insertion in the TfMYB1 second intron was found to cause a mutant torenia phenotype by reducing expressions of flavonoid biosynthetic genes, including CHS, F3H, DFR, ANS, and UDP-glucose: flavonoid glucosyltransferase (UFGT)[ 35].

Indeed, Sphk-1 inhibition by DHS reduced expression of these proteins in infected macrophages (Fig. 3A, B and C).

These results therefore led us to investigate whether such a defect could be explained by constitutively reduced expression of one or more of the nucleases responsible for apoptotic DNA fragmentation.

This effect was evidenced by significantly reduced expression of proinflammatory cytokines, such as nuclear factor– κB, interleukin-1 β and interleukin-6.

The addition of IL-21 to IL-15 or IL-2 can modify the pattern of the KIR receptors and inhibit NKp44 expression by reducing the expression of the adaptor DAP-12.