Sentence examples for by reduced expression and from inspiring English sources

In addition, tECM-supplemented constructs displayed enhanced mechanical strength, accompanied by reduced expression and activity of MMPs in the seeded hASCs, indicating a regulatory activity of tECM in cell-mediated scaffold remodeling.

Decreased mitochondrial GK activity in βIRKOs could be explained, in part, by reduced expression and altered phosphorylation of BADS.

Liang et al. have recently observed that increased CD36 protein expression on mouse macrophages may be connected with defective insulin signaling in these cells as estimated by reduced expression and signaling of insulin receptors [ 9].

This review reports current knowledge on the impact of oxidative stress in RBC modifications with the surface appearance of senescent signals characterized by reduced expression of CD47 and glycophorin A and higher externalization of phosphatidylserine.

Our results indicated that the development of cisplatin resistance in gastric cancer cells might be a synergetic effect associated with less accumulation of intracellular cisplatin by reduced expression of CTR1 and increased MRP2, and enhanced ability of cisplatin detoxification by GSH.

Reduced expression of UCP1 was accompanied by reduced expression of PGC1α and Cidea (Figure 6B).

Consequently, Bortezomib counteracts Taxol-induced mitotic arrest and polyploidy, as shown by reduced expression of PLK1 and phosphorylated histone H3.

Phenotypic alterations, marked by reduced expression of TCR and CD5 in Vav1-/ DP thymocytes, and elevated HSA in SP thymocytes, were also reversed in Cbl-/-Vav1-/ cells (Fig. 1E).

BMP2 and FGF2 act as proliferative factors as indicated by reduced expression of ALP and POSTN, whereas IGF1 exhibits a more subtle picture: the Wingless und Int-1 (Wnt) signalling pathway and the Smad pathway, but not p38 mitogen-activated protein (MAP) kinase signalling, were shown to be activated by IGF1, leading to proliferation and differentiation of the cells.

This reduction in inflammation was accompanied by reduced expression of Mmp9 and Mmp12 transcripts in BAL fluid cells as compared with nCB-challenged mice.

This is accompanied by reduced expression of Shh and pathway target genes in the developing ventral forebrains of such mice at specific stages.